Human ES- and iPS-Derived Myogenic Progenitors Restore Dystrophin and Improve Contractility upon Transplantation in Dystrophic Mice

A major obstacle in the application of cell-based therapies for the treatment of neuromuscular disorders is obtaining the appropriate number of stem/progenitor cells to produce effective engraftment. The use of embryonic stem (ES) or induced pluripotent stem (iPS) cells could overcome this hurdle. H...

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Autori principali: Darabi, Radbod, Arpke, Robert W., Irion, Stefan, Dimos, John T., Grskovic, Marica, Kyba, Michael, Perlingeiro, Rita C. R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348507/
https://ncbi.nlm.nih.gov/pubmed/22560081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.02.015
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