Expansion and Purification Are Critical for the Therapeutic Application of Pluripotent Stem Cell-Derived Myogenic Progenitors

Recent reports have documented the differentiation of human pluripotent stem cells toward the skeletal myogenic lineage using transgene- and cell purification-free approaches. Although these protocols generate myocytes, they have not demonstrated scalability, safety, and in vivo engraftment, which a...

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Bibliographic Details
Published in:Stem Cell Reports
Main Authors: Kim, Jaemin, Magli, Alessandro, Chan, Sunny S.K., Oliveira, Vanessa K.P., Wu, Jianbo, Darabi, Radbod, Kyba, Michael, Perlingeiro, Rita C.R.
Format: Artigo
Language:Inglês
Published: Elsevier 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511038/
https://ncbi.nlm.nih.gov/pubmed/28528701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.04.022
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