Transplantation studies reveal internuclear transfer of toxic RNA in engrafted muscles of myotonic dystrophy 1 mice

BACKGROUND: Stem cell transplantation represents a potential therapeutic option for muscular dystrophies (MD). However, to date, most reports have utilized mouse models for recessive types of MD. Here we performed studies to determine whether myotonic dystrophy 1 (DM1), an autosomal dominant type of...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Mondragon-Gonzalez, Ricardo, Azzag, Karim, Selvaraj, Sridhar, Yamamoto, Ami, Perlingeiro, Rita C.R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796515/
https://ncbi.nlm.nih.gov/pubmed/31446083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.08.031
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