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Role of p53 in the Regulation of Cellular Senescence
The p53 transcription factor plays a critical role in cellular responses to stress. Its activation in response to DNA damage leads to cell growth arrest, allowing for DNA repair, or directs cellular senescence or apoptosis, thereby maintaining genome integrity. Senescence is a permanent cell-cycle a...
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| 出版年: | Biomolecules |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7175209/ https://ncbi.nlm.nih.gov/pubmed/32182711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10030420 |
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