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Regulation of cellular senescence via the FOXO4‐p53 axis

Forkhead box O (FOXO) and p53 proteins are transcription factors that regulate diverse signalling pathways to control cell cycle, apoptosis and metabolism. In the last decade both FOXO and p53 have been identified as key players in aging, and their misregulation is linked to numerous diseases includ...

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Detalles Bibliográficos
Publicado en:FEBS Lett
Main Authors: Bourgeois, Benjamin, Madl, Tobias
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033032/
https://ncbi.nlm.nih.gov/pubmed/29683489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13057
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