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Regulation of cellular senescence via the FOXO4‐p53 axis

Forkhead box O (FOXO) and p53 proteins are transcription factors that regulate diverse signalling pathways to control cell cycle, apoptosis and metabolism. In the last decade both FOXO and p53 have been identified as key players in aging, and their misregulation is linked to numerous diseases includ...

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Bibliographic Details
Published in:FEBS Lett
Main Authors: Bourgeois, Benjamin, Madl, Tobias
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033032/
https://ncbi.nlm.nih.gov/pubmed/29683489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13057
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