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Targeting cellular senescence in cancer and aging: roles of p53 and its isoforms

Cellular senescence and the associated secretory phenotype (SASP) promote disease in the aged population. Targeting senescent cells by means of removal, modulation of SASP or through cellular reprogramming represents a novel therapeutic avenue for treating cancer- and age-related diseases such as ne...

詳細記述

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書誌詳細
出版年:Carcinogenesis
主要な著者: Beck, Jessica, Turnquist, Casmir, Horikawa, Izumi, Harris, Curtis
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422622/
https://ncbi.nlm.nih.gov/pubmed/32619002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgaa071
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