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Targeting cellular senescence in cancer and aging: roles of p53 and its isoforms

Cellular senescence and the associated secretory phenotype (SASP) promote disease in the aged population. Targeting senescent cells by means of removal, modulation of SASP or through cellular reprogramming represents a novel therapeutic avenue for treating cancer- and age-related diseases such as ne...

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Bibliografische gegevens
Gepubliceerd in:Carcinogenesis
Hoofdauteurs: Beck, Jessica, Turnquist, Casmir, Horikawa, Izumi, Harris, Curtis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422622/
https://ncbi.nlm.nih.gov/pubmed/32619002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgaa071
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