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Targeting cellular senescence in cancer and aging: roles of p53 and its isoforms
Cellular senescence and the associated secretory phenotype (SASP) promote disease in the aged population. Targeting senescent cells by means of removal, modulation of SASP or through cellular reprogramming represents a novel therapeutic avenue for treating cancer- and age-related diseases such as ne...
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| Pubblicato in: | Carcinogenesis |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7422622/ https://ncbi.nlm.nih.gov/pubmed/32619002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgaa071 |
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