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The Δ133p53 Isoforms, Tuners of the p53 Pathway

SIMPLE SUMMARY: TP53, the most frequently mutated gene in human cancers, has a key role in the maintenance of the genetic stability and, thus, in preventing tumor development. The p53-dependent responses were long thought to be solely driven by canonical p53α. However, it is now known that TP53 phys...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Joruiz, Sebastien M., Beck, Jessica A., Horikawa, Izumi, Harris, Curtis C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698932/
https://ncbi.nlm.nih.gov/pubmed/33218139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113422
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