Astrocyte senescence and SASP in neurodegeneration: tau joins the loop

Tau accumulation is a core component of Alzheimer’s disease and other neurodegenerative tauopathies. While tau’s impact on neurons is a major area of research, the effect of extracellular tau on astrocytes is largely unknown. This article summarizes our recent studies showing that astrocyte senescen...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Ungerleider, Kyra, Beck, Jessica, Lissa, Delphine, Turnquist, Casmir, Horikawa, Izumi, Harris, Brent T., Harris, Curtis C.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098067/
https://ncbi.nlm.nih.gov/pubmed/33818291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2021.1909260
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