Insufficient Antigen Presentation Due to Viral Immune Evasion Explains Lethal Cytomegalovirus Organ Disease After Allogeneic Hematopoietic Cell Transplantation

Reactivation of latent cytomegalovirus (CMV) poses a clinical problem in transiently immunocompromised recipients of hematopoietic cell (HC) transplantation (HCT) by viral histopathology that results in multiple organ manifestations. Compared to autologous HCT and to syngeneic HCT performed with ide...

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Veröffentlicht in:Front Cell Infect Microbiol
Hauptverfasser: Holtappels, Rafaela, Schader, Sina I., Oettel, Oliver, Podlech, Jürgen, Seckert, Christof K., Reddehase, Matthias J., Lemmermann, Niels A. W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Cellular and Infection Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174590/
https://ncbi.nlm.nih.gov/pubmed/32351904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.00157
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