Reconstitution of CD8 T Cells Protective against Cytomegalovirus in a Mouse Model of Hematopoietic Cell Transplantation: Dynamics and Inessentiality of Epitope Immunodominance

Successful reconstitution of cytomegalovirus (CMV)-specific CD8(+) T cells by hematopoietic cell transplantation (HCT) gives a favorable prognosis for the control of CMV reactivation and prevention of CMV disease after hematoablative therapy of hematopoietic malignancies. In the transient immunocomp...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Holtappels, Rafaela, Lemmermann, Niels A. W., Podlech, Jürgen, Ebert, Stefan, Reddehase, Matthias J.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2016
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905951/
https://ncbi.nlm.nih.gov/pubmed/27379095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00232
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