The Immune Evasion Paradox: Immunoevasins of Murine Cytomegalovirus Enhance Priming of CD8 T Cells by Preventing Negative Feedback Regulation

Cytomegaloviruses express glycoproteins that interfere with antigen presentation to CD8 T cells. Although the molecular modes of action of these “immunoevasins” differ between cytomegalovirus species, the convergent biological outcome is an inhibition of the recognition of infected cells. In murine...

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Autors principals: Böhm, Verena, Simon, Christian O., Podlech, Jürgen, Seckert, Christof K., Gendig, Dorothea, Deegen, Petra, Gillert-Marien, Dorothea, Lemmermann, Niels A. W., Holtappels, Rafaela, Reddehase, Matthias J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583666/
https://ncbi.nlm.nih.gov/pubmed/18815306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01510-08
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