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Lentiviral Vector Design for Multiple shRNA Expression and Durable HIV-1 Inhibition
Human immunodeficiency virus type 1 (HIV-1) replication in T cells can be inhibited by RNA interference (RNAi) through short hairpin RNA (shRNA) expression from a lentiviral vector. However, for the development of a durable RNAi-based gene therapy against HIV-1, multiple shRNAs need to be expressed...
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| Publicado no: | Mol Ther |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society of Gene Therapy. Published by Elsevier Inc.
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7172400/ https://ncbi.nlm.nih.gov/pubmed/18180777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.mt.6300382 |
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