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Human Immunodeficiency Virus Type 1 Escape Is Restricted When Conserved Genome Sequences Are Targeted by RNA Interference

RNA interference (RNAi) is a cellular mechanism in which small interfering RNAs (siRNAs) mediate sequence-specific gene silencing by cleaving the targeted mRNA. RNAi can be used as an antiviral approach to silence the human immunodeficiency virus type 1 (HIV-1) through stable expression of short-hai...

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Autors principals: von Eije, Karin Jasmijn, Brake, Olivier ter, Berkhout, Ben
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258968/
https://ncbi.nlm.nih.gov/pubmed/18077712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02035-07
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