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A novel approach for inhibition of HIV-1 by RNA interference: counteracting viral escape with a second generation of siRNAs

RNA interference (RNAi) is an evolutionary conserved gene silencing mechanism in which small interfering RNA (siRNA) mediates the sequence specific degradation of mRNA. The recent discovery that exogenously delivered siRNA can trigger RNAi in mammalian cells raises the possibility to use this techno...

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Bibliografske podrobnosti
Main Authors: ter Brake, Olivier, Berkhout, Ben
Format: Artigo
Jezik:Inglês
Izdano: Library Publishing Media 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737200/
https://ncbi.nlm.nih.gov/pubmed/19771206
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