Preclinical In Vivo Evaluation of the Safety of a Multi-shRNA-based Gene Therapy Against HIV-1

Highly active antiretroviral therapy (HAART) has significantly improved the quality of life and the life expectancy of HIV-infected individuals. Still, drug-induced side effects and emergence of drug-resistant viral variants remain important issues that justify the exploration of alternative therape...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Centlivre, Mireille, Legrand, Nicolas, Klamer, Sofieke, Liu, Ying Poi, Eije, Karin Jasmijn von, Bohne, Martino, Rijnstra, Esther Siteur-van, Weijer, Kees, Blom, Bianca, Voermans, Carlijn, Spits, Hergen, Berkhout, Ben
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808742/
https://ncbi.nlm.nih.gov/pubmed/24002730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2013.48
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