Potent USP10/13 antagonist spautin‐1 suppresses melanoma growth via ROS‐mediated DNA damage and exhibits synergy with cisplatin

Malignant melanoma is one of the most invasive tumours. However, effective therapeutic strategies are limited, and overall survival rates remain low. By utilizing transcriptomic profiling, tissue array and molecular biology, we revealed that two key ubiquitin‐specific proteases (USPs), ubiquitin‐spe...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Guo, Jia, Zhang, JiangLing, Liang, Long, Liu, Nian, Qi, Min, Zhao, Shuang, Su, Juan, Liu, Jing, Peng, Cong, Chen, Xiang, Liu, Hong
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171391/
https://ncbi.nlm.nih.gov/pubmed/32129945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15093
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