Potent USP10/13 antagonist spautin‐1 suppresses melanoma growth via ROS‐mediated DNA damage and exhibits synergy with cisplatin

Malignant melanoma is one of the most invasive tumours. However, effective therapeutic strategies are limited, and overall survival rates remain low. By utilizing transcriptomic profiling, tissue array and molecular biology, we revealed that two key ubiquitin‐specific proteases (USPs), ubiquitin‐spe...

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Bibliografiska uppgifter
I publikationen:J Cell Mol Med
Huvudupphovsmän: Guo, Jia, Zhang, JiangLing, Liang, Long, Liu, Nian, Qi, Min, Zhao, Shuang, Su, Juan, Liu, Jing, Peng, Cong, Chen, Xiang, Liu, Hong
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2020
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171391/
https://ncbi.nlm.nih.gov/pubmed/32129945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15093
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