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The role of propofol hydroxyl group in 5-lipoxygenase recognition
Propofol is a clinically important intravenous anesthetic. We previously reported that it directly inhibited 5-lipoxygenase (5-LOX), a key enzyme for leukotriene biosynthesis. Because the hydroxyl group in propofol (propofol 1-hydroxyl) is critical for its anesthetic effect, we examined if its prese...
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| Gepubliceerd in: | Biochem Biophys Res Commun |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7167355/ https://ncbi.nlm.nih.gov/pubmed/32171526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2020.03.037 |
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