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Propofol Shares the Binding Site with Isoflurane and Sevoflurane on Leukocyte Function-Associated Antigen-1

BACKGROUND: We previously demonstrated that propofol interacted with the leukocyte adhesion molecule leukocyte function–associated antigen-1 (LFA-1) and inhibited the production of interleukin-2 via LFA-1 in a dependent manner. However, the binding site(s) of propofol on LFA-1 remains unknown. METHO...

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Detalhes bibliográficos
Main Authors: Yuki, Koichi, Bu, Weiming, Xi, Jin, Shimaoka, Motomu, Eckenhoff, Roderic
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844542/
https://ncbi.nlm.nih.gov/pubmed/23960033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e3182a00ae0
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