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Isoflurane binds and stabilizes a closed conformation of the leukocyte function-associated antigen-1
We previously demonstrated that isoflurane targets lymphocyte function-associated antigen-1 (LFA-1), a critical adhesion molecule for leukocyte arrest. However, it remains to be determined how isoflurane interacts with the full ectodomain LFA-1 and modulates its conformation and function. Isoflurane...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3475260/ https://ncbi.nlm.nih.gov/pubmed/22815384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-212746 |
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