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Isoflurane binds and stabilizes a closed conformation of the leukocyte function-associated antigen-1

We previously demonstrated that isoflurane targets lymphocyte function-associated antigen-1 (LFA-1), a critical adhesion molecule for leukocyte arrest. However, it remains to be determined how isoflurane interacts with the full ectodomain LFA-1 and modulates its conformation and function. Isoflurane...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Yuki, Koichi, Bu, Weiming, Xi, Jin, Sen, Mehmet, Shimaoka, Motomu, Eckenhoff, Roderic G.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Federation of American Societies for Experimental Biology 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475260/
https://ncbi.nlm.nih.gov/pubmed/22815384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-212746
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