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Sevoflurane Binds and Allosterically Blocks Integrin Lymphocyte Function-associated Antigen-1

BACKGROUND: Volatile anesthetics have been shown to modify immune cell functions via several mechanisms, some of which have been only partially elucidated. We demonstrated that isoflurane inhibits primary leukocyte integrin lymphocyte function-associated antigen-1 (LFA-1) by binding to the allosteri...

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Detalhes bibliográficos
Publicado no:Anesthesiology
Main Authors: Yuki, Koichi, Astrof, Nathan S., Bracken, Clay, Soriano, Sulpicio G., Shimaoka, Motomu
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209785/
https://ncbi.nlm.nih.gov/pubmed/20693879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3181e89a77
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