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Structural basis of blocking integrin activation and deactivation for anti-inflammation
Integrins mediate leukocyte accumulation to the sites of inflammation, thereby enhancing their potential as an important therapeutic target for inflammatory disorders. Integrin activation triggered by inflammatory mediators or signaling pathway is a key step to initiate leukocyte migration to inflam...
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| 發表在: | J Biomed Sci |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4495637/ https://ncbi.nlm.nih.gov/pubmed/26152212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-015-0159-6 |
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