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Sevoflurane Binds and Allosterically Blocks Integrin Lymphocyte Function-associated Antigen-1
BACKGROUND: Volatile anesthetics have been shown to modify immune cell functions via several mechanisms, some of which have been only partially elucidated. We demonstrated that isoflurane inhibits primary leukocyte integrin lymphocyte function-associated antigen-1 (LFA-1) by binding to the allosteri...
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| Publicado en: | Anesthesiology |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5209785/ https://ncbi.nlm.nih.gov/pubmed/20693879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3181e89a77 |
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