Cargando...
Covalent Modification of the Flavin in Proline Dehydrogenase by Thiazolidine-2-Carboxylate
Proline dehydrogenase (PRODH) catalyzes the first step of proline catabolism, the FAD-dependent 2-electron oxidation of l-proline to Δ(1)-pyrroline-5-carboxylate. PRODH has emerged as a possible cancer therapy target, and thus the inhibition of PRODH is of interest. Here we show that the proline ana...
Guardado en:
| Publicado en: | ACS Chem Biol |
|---|---|
| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2020
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7166166/ https://ncbi.nlm.nih.gov/pubmed/32159324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00935 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|