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Structure of the Proline Utilization A Proline Dehydrogenase Domain Inactivated by N-propargylglycine Provides Insight into Conformational Changes Induced by Substrate Binding and Flavin Reduction(,)

Proline utilization A (PutA) from Escherichia coli is a flavoprotein that has mutually exclusive roles as a transcriptional repressor of the put regulon and a membrane-associated enzyme that catalyzes the oxidation of proline to glutamate. Previous studies have shown that the binding of proline in t...

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Detalhes bibliográficos
Main Authors: Srivastava, Dhiraj, Zhu, Weidong, Johnson, William H., Whitman, Christian P., Becker, Donald F., Tanner, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727237/
https://ncbi.nlm.nih.gov/pubmed/19994913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901717s
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