Structural Basis for the Substrate Inhibition of Proline Utilization A by Proline

Proline utilization A (PutA) is a bifunctional flavoenzyme that catalyzes the two-step oxidation of l-proline to l-glutamate using spatially separated proline dehydrogenase (PRODH) and l-glutamate-γ-semialdehyde dehydrogenase (GSALDH) active sites. Substrate inhibition of the coupled PRODH-GSALDH re...

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Publicado en:Molecules
Autores principales: Korasick, David A., Pemberton, Travis A., Arentson, Benjamin W., Becker, Donald F., Tanner, John J.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786444/
https://ncbi.nlm.nih.gov/pubmed/29295473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23010032
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