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Structural Basis for the Inactivation of Thermus thermophilus Proline Dehydrogenase by N-Propargylglycine
The flavoenzyme proline dehydrogenase catalyzes the first step of proline catabolism, the oxidation of proline to pyrroline-5-carboxylate. Here we report the first crystal structure of an irreversibly inactivated proline dehydrogenase. The 1.9 Å resolution structure of Thermus thermophilus proline d...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2708978/ https://ncbi.nlm.nih.gov/pubmed/18426222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800055w |
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