BMP10-mediated ALK1 signaling is continuously required for vascular development and maintenance

Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular disorder characterized by development of high-flow arteriovenous malformations (AVMs) that can lead to stroke or high-output heart failure. HHT2 is caused by heterozygous mutations in ACVRL1, which encodes an endothelial c...

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Bibliografske podrobnosti
izdano v:Angiogenesis
Main Authors: Capasso, Teresa L., Li, Bijun, Volek, Harry J., Khalid, Waqas, Rochon, Elizabeth R., Anbalagan, Arulselvi, Herdman, Chelsea, Yost, H. Joseph, Villanueva, Flordeliza S., Kim, Kang, Roman, Beth L.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7165044/
https://ncbi.nlm.nih.gov/pubmed/31828546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-019-09701-0
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