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Alk1 controls arterial endothelial cell migration in lumenized vessels
Heterozygous loss of the arterial-specific TGFβ type I receptor, activin receptor-like kinase 1 (ALK1; ACVRL1), causes hereditary hemorrhagic telangiectasia (HHT). HHT is characterized by development of fragile, direct connections between arteries and veins, or arteriovenous malformations (AVMs). Ho...
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| Publicado no: | Development |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4958337/ https://ncbi.nlm.nih.gov/pubmed/27287800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.135392 |
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