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Context-specific interactions between Notch and ALK1 cannot explain ALK1-associated arteriovenous malformations

AIMS: Notch and activin receptor-like kinase 1 (ALK1) have been implicated in arterial specification, angiogenic tip/stalk cell differentiation, and development of arteriovenous malformations (AVMs), and ALK1 can cooperate with Notch to up-regulate expression of Notch target genes in cultured endoth...

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Dades bibliogràfiques
Publicat a:Cardiovasc Res
Autors principals: Rochon, Elizabeth R., Wright, Daniel S., Schubert, Max M., Roman, Beth L.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498135/
https://ncbi.nlm.nih.gov/pubmed/25969392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvv148
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