Circulating Bmp10 acts through endothelial Alk1 to mediate flow-dependent arterial quiescence

Blood flow plays crucial roles in vascular development, remodeling and homeostasis, but the molecular pathways required for transducing flow signals are not well understood. In zebrafish embryos, arterial expression of activin receptor-like kinase 1 (alk1), which encodes a TGFβ family type I recepto...

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Bibliografske podrobnosti
Main Authors: Laux, Derek W., Young, Sarah, Donovan, James P., Mansfield, Corrine J., Upton, Paul D., Roman, Beth L.
Format: Artigo
Jezik:Inglês
Izdano: Company of Biologists 2013
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737721/
https://ncbi.nlm.nih.gov/pubmed/23863480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.095307
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