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BMP10-mediated ALK1 signaling is continuously required for vascular development and maintenance
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular disorder characterized by development of high-flow arteriovenous malformations (AVMs) that can lead to stroke or high-output heart failure. HHT2 is caused by heterozygous mutations in ACVRL1, which encodes an endothelial c...
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| Publicado no: | Angiogenesis |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7165044/ https://ncbi.nlm.nih.gov/pubmed/31828546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-019-09701-0 |
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