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Short-term Calorie Restriction and 17α-Estradiol Administration Elicit Divergent Effects on Proteostatic Processes and Protein Content in Metabolically Active Tissues

17α-Estradiol (17α-E2) is a “non-feminizing” estrogen that extends life span in male, but not female, mice. We recently reported that 17α-E2 had robust beneficial effects on metabolic and inflammatory parameters in aged male mice. However, it remains unclear if 17α-E2 also delays other “hallmarks” o...

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Bibliografiske detaljer
Udgivet i:J Gerontol A Biol Sci Med Sci
Main Authors: Miller, Benjamin F, Pharaoh, Gavin A, Hamilton, Karyn L, Peelor, Fredrick F, Kirkland, James L, Freeman, Willard M, Mann, Shivani N, Kinter, Michael, Price, John C, Stout, Michael B
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
THE JOURNAL OF GERONTOLOGY: Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164531/
https://ncbi.nlm.nih.gov/pubmed/31074767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glz113
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