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Estradiol Elicits Proapoptotic and Antiproliferative Effects in Human Trophoblast Cells

During the first trimester of pregnancy, appropriate regulation of estradiol (E2) is essential for normal placental development. Previous studies demonstrate that premature elevation in E2 concentrations can lead to abnormal placentation, but have not fully elaborated the mechanism of this effect in...

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Detalhes bibliográficos
Publicado no:Biol Reprod
Main Authors: Patel, Shivali, Kilburn, Brian, Imudia, Anthony, Armant, D. Randall, Skafar, Debra F.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710192/
https://ncbi.nlm.nih.gov/pubmed/26246219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.115.129114
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