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Estradiol Elicits Proapoptotic and Antiproliferative Effects in Human Trophoblast Cells

During the first trimester of pregnancy, appropriate regulation of estradiol (E2) is essential for normal placental development. Previous studies demonstrate that premature elevation in E2 concentrations can lead to abnormal placentation, but have not fully elaborated the mechanism of this effect in...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biol Reprod
Prif Awduron: Patel, Shivali, Kilburn, Brian, Imudia, Anthony, Armant, D. Randall, Skafar, Debra F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for the Study of Reproduction, Inc. 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710192/
https://ncbi.nlm.nih.gov/pubmed/26246219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.115.129114
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