Health benefits attributed to 17α-estradiol, a lifespan-extending compound, are mediated through estrogen receptor α

Metabolic dysfunction underlies several chronic diseases, many of which are exacerbated by obesity. Dietary interventions can reverse metabolic declines and slow aging, although compliance issues remain paramount. 17α-estradiol treatment improves metabolic parameters and slows aging in male mice. Th...

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Detalles Bibliográficos
Publicado en:eLife
Autores principales: Mann, Shivani N, Hadad, Niran, Nelson Holte, Molly, Rothman, Alicia R, Sathiaseelan, Roshini, Ali Mondal, Samim, Agbaga, Martin-Paul, Unnikrishnan, Archana, Subramaniam, Malayannan, Hawse, John, Huffman, Derek M, Freeman, Willard M, Stout, Michael B
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Medicine
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744101/
https://ncbi.nlm.nih.gov/pubmed/33289482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59616
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