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Inhibition of Chikungunya virus by an adenosine analog targeting the SAM‐dependent nsP1 methyltransferase

Alphaviruses, including Chikungunya (CHIKV) and Venezuelan equine encephalitis virus (VEEV), are among the leading causes of recurrent epidemics all over the world. Alphaviral nonstructural protein 1 (nsP1) orchestrates the capping of nascent viral RNA via its S‐adenosyl methionine‐dependent N‐7‐met...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Mudgal, Rajat, Mahajan, Supreeti, Tomar, Shailly
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164056/
https://ncbi.nlm.nih.gov/pubmed/31623018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13642
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