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The viral capping enzyme nsP1: a novel target for the inhibition of chikungunya virus infection
The chikungunya virus (CHIKV) has become a substantial global health threat due to its massive re-emergence, the considerable disease burden and the lack of vaccines or therapeutics. We discovered a novel class of small molecules ([1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-ones) with potent in vitro acti...
Shranjeno v:
| izdano v: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4992889/ https://ncbi.nlm.nih.gov/pubmed/27545976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31819 |
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