Chikungunya virus nsP1 interacts directly with nsP2 and modulates its ATPase activity

Chikungunya virus (CHIKV) is a mosquito-borne virus, which has created an alarming threat in the world due to unavailability of vaccine and antiviral compounds. The CHIKV nsP2 contains ATPase, RTPase, helicase and protease activities, whereas, nsP1 is a viral capping enzyme. In alphaviruses, the fou...

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Udgivet i:Sci Rep
Main Authors: Kumar, Sameer, Kumar, Abhishek, Mamidi, Prabhudutta, Tiwari, Atul, Kumar, Sriram, Mayavannan, Animamalar, Mudulli, Sagarika, Singh, Ajit Kumar, Subudhi, Bharat Bhusan, Chattopadhyay, Soma
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773547/
https://ncbi.nlm.nih.gov/pubmed/29348627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19295-0
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