P38 and JNK Mitogen-Activated Protein Kinases Interact With Chikungunya Virus Non-structural Protein-2 and Regulate TNF Induction During Viral Infection in Macrophages

Chikungunya virus (CHIKV), a mosquito-borne Alphavirus, is endemic in different parts of the globe. The host macrophages are identified as the major cellular reservoirs of CHIKV during infection and this virus triggers robust TNF production in the host macrophages, which might be a key mediator of v...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Nayak, Tapas Kumar, Mamidi, Prabhudutta, Sahoo, Subhransu Sekhar, Kumar, P. Sanjai, Mahish, Chandan, Chatterjee, Sanchari, Subudhi, Bharat Bhusan, Chattopadhyay, Soma, Chattopadhyay, Subhasis
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6473476/
https://ncbi.nlm.nih.gov/pubmed/31031770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00786
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