P38 and JNK Mitogen-Activated Protein Kinases Interact With Chikungunya Virus Non-structural Protein-2 and Regulate TNF Induction During Viral Infection in Macrophages

Chikungunya virus (CHIKV), a mosquito-borne Alphavirus, is endemic in different parts of the globe. The host macrophages are identified as the major cellular reservoirs of CHIKV during infection and this virus triggers robust TNF production in the host macrophages, which might be a key mediator of v...

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Vydáno v:Front Immunol
Hlavní autoři: Nayak, Tapas Kumar, Mamidi, Prabhudutta, Sahoo, Subhransu Sekhar, Kumar, P. Sanjai, Mahish, Chandan, Chatterjee, Sanchari, Subudhi, Bharat Bhusan, Chattopadhyay, Soma, Chattopadhyay, Subhasis
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6473476/
https://ncbi.nlm.nih.gov/pubmed/31031770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00786
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