Analysis of chikungunya virus proteins reveals that non-structural proteins nsP2 and nsP3 exhibit RNA interference (RNAi) suppressor activity

RNAi pathway is an antiviral defence mechanism employed by insects that result in degradation of viral RNA thereby curbing infection. Several viruses including flaviviruses encode viral suppressors of RNAi (VSRs) to counteract the antiviral RNAi pathway. Till date, no VSR has been reported in alphav...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Mathur, Kalika, Anand, Abhishek, Dubey, Sunil Kumar, Sanan-Mishra, Neeti, Bhatnagar, Raj K., Sunil, Sujatha
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5128919/
https://ncbi.nlm.nih.gov/pubmed/27901124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38065
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