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Analysis of chikungunya virus proteins reveals that non-structural proteins nsP2 and nsP3 exhibit RNA interference (RNAi) suppressor activity

RNAi pathway is an antiviral defence mechanism employed by insects that result in degradation of viral RNA thereby curbing infection. Several viruses including flaviviruses encode viral suppressors of RNAi (VSRs) to counteract the antiviral RNAi pathway. Till date, no VSR has been reported in alphav...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Mathur, Kalika, Anand, Abhishek, Dubey, Sunil Kumar, Sanan-Mishra, Neeti, Bhatnagar, Raj K., Sunil, Sujatha
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5128919/
https://ncbi.nlm.nih.gov/pubmed/27901124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38065
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