Structural insights into RNA recognition by the Chikungunya virus nsP2 helicase

Chikungunya virus (CHIKV) is transmitted to humans through mosquitoes and causes Chikungunya fever. Nonstructural protein 2 (nsP2) exhibits the protease and RNA helicase activities that are required for viral RNA replication and transcription. Unlike for the C-terminal protease, the structure of the...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Law, Yee-Song, Utt, Age, Tan, Yaw Bia, Zheng, Jie, Wang, Sainan, Chen, Ming Wei, Griffin, Patrick R., Merits, Andres, Luo, Dahai
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511008/
https://ncbi.nlm.nih.gov/pubmed/31000599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1900656116
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