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SAM/SAH Analogs as Versatile Tools for SAM-Dependent Methyltransferases
S -Adenosyl-L-methionine (SAM) is a sulfonium molecule with a structural hybrid of methionine and adenosine. As the second largest cofactor in the human body, its major function is to serve as methyl donor for SAM-dependent methyltransferases (MTases). The resultant transmethylation of biomolecules...
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| Veröffentlicht in: | ACS Chem Biol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5772741/ https://ncbi.nlm.nih.gov/pubmed/26540123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00812 |
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