Directed Evolution of a Halide Methyltransferase Enables Biocatalytic Synthesis of Diverse SAM Analogs

Biocatalytic alkylations are important reactions to obtain chemo‐, regio‐ and stereoselectively alkylated compounds. This can be achieved using S‐adenosyl‐l‐methionine (SAM)‐dependent methyltransferases and SAM analogs. It was recently shown that a halide methyltransferase (HMT) from Chloracidobacte...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Angew Chem Int Ed Engl
Autores principales: Tang, Qingyun, Grathwol, Christoph W., Aslan‐Üzel, Aşkın S., Wu, Shuke, Link, Andreas, Pavlidis, Ioannis V., Badenhorst, Christoffel P. S., Bornscheuer, Uwe T.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839550/
https://ncbi.nlm.nih.gov/pubmed/33108827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202013871
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares