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Inhibition of Chikungunya virus by an adenosine analog targeting the SAM‐dependent nsP1 methyltransferase

Alphaviruses, including Chikungunya (CHIKV) and Venezuelan equine encephalitis virus (VEEV), are among the leading causes of recurrent epidemics all over the world. Alphaviral nonstructural protein 1 (nsP1) orchestrates the capping of nascent viral RNA via its S‐adenosyl methionine‐dependent N‐7‐met...

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Détails bibliographiques
Publié dans:FEBS Lett
Auteurs principaux: Mudgal, Rajat, Mahajan, Supreeti, Tomar, Shailly
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164056/
https://ncbi.nlm.nih.gov/pubmed/31623018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13642
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