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Inhibition of Chikungunya virus by an adenosine analog targeting the SAM‐dependent nsP1 methyltransferase

Alphaviruses, including Chikungunya (CHIKV) and Venezuelan equine encephalitis virus (VEEV), are among the leading causes of recurrent epidemics all over the world. Alphaviral nonstructural protein 1 (nsP1) orchestrates the capping of nascent viral RNA via its S‐adenosyl methionine‐dependent N‐7‐met...

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Udgivet i:FEBS Lett
Main Authors: Mudgal, Rajat, Mahajan, Supreeti, Tomar, Shailly
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164056/
https://ncbi.nlm.nih.gov/pubmed/31623018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13642
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