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Inhibition of Chikungunya virus by an adenosine analog targeting the SAM‐dependent nsP1 methyltransferase

Alphaviruses, including Chikungunya (CHIKV) and Venezuelan equine encephalitis virus (VEEV), are among the leading causes of recurrent epidemics all over the world. Alphaviral nonstructural protein 1 (nsP1) orchestrates the capping of nascent viral RNA via its S‐adenosyl methionine‐dependent N‐7‐met...

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Dettagli Bibliografici
Pubblicato in:FEBS Lett
Autori principali: Mudgal, Rajat, Mahajan, Supreeti, Tomar, Shailly
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164056/
https://ncbi.nlm.nih.gov/pubmed/31623018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13642
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