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SAM/SAH Analogs as Versatile Tools for SAM-Dependent Methyltransferases

S -Adenosyl-L-methionine (SAM) is a sulfonium molecule with a structural hybrid of methionine and adenosine. As the second largest cofactor in the human body, its major function is to serve as methyl donor for SAM-dependent methyltransferases (MTases). The resultant transmethylation of biomolecules...

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Bibliografiske detaljer
Udgivet i:ACS Chem Biol
Main Authors: Zhang, Jing, Zheng, Yujun George
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772741/
https://ncbi.nlm.nih.gov/pubmed/26540123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00812
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