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Placental transporter‐mediated drug interactions and offspring congenital anomalies

AIMS: P‐glycoprotein (P‐gp) and breast cancer resistance protein (BCRP) are efflux transporters expressed in the placenta, limiting their substrates from reaching the foetus. Our aim was to investigate if concomitant prenatal exposure to several substrates or inhibitors of these transporters increas...

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Bibliografske podrobnosti
izdano v:Br J Clin Pharmacol
Main Authors: Ellfolk, Maria, Tornio, Aleksi, Niemi, Mikko, Leinonen, Maarit K., Lahesmaa‐Korpinen, Anna‐Maria, Malm, Heli
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7163376/
https://ncbi.nlm.nih.gov/pubmed/31823387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14191
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