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Placental transporter‐mediated drug interactions and offspring congenital anomalies

AIMS: P‐glycoprotein (P‐gp) and breast cancer resistance protein (BCRP) are efflux transporters expressed in the placenta, limiting their substrates from reaching the foetus. Our aim was to investigate if concomitant prenatal exposure to several substrates or inhibitors of these transporters increas...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Ellfolk, Maria, Tornio, Aleksi, Niemi, Mikko, Leinonen, Maarit K., Lahesmaa‐Korpinen, Anna‐Maria, Malm, Heli
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7163376/
https://ncbi.nlm.nih.gov/pubmed/31823387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14191
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