Maternal use of drug substrates of placental transporters and the effect of transporter-mediated drug interactions on the risk of congenital anomalies

BACKGROUND: A number of transporter proteins are expressed in the placenta, and they facilitate the placental transfer of drugs. The inhibition of P-glycoprotein (P-gp) was previously found to be associated with an increase in the risk of congenital anomalies caused by drug substrates of this transp...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Daud, Aizati N. A., Bergman, Jorieke E. H., Oktora, Monika P., Kerstjens-Frederikse, Wilhelmina S., Groen, Henk, Bos, Jens H., Hak, Eelko, Wilffert, Bob
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348032/
https://ncbi.nlm.nih.gov/pubmed/28288183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173530
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires